New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

The developmental period is a critical window during which environmental cues interact with the genome to shape lifelong trajectories of health and disease.

Analyzing population-level chromatin accessibility data shows added benefit over utilizing only gene expression data in elucidating the genetic mechanism of disease-associated variants.

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...