Last year, the Broncos went 10-7 in coach Sean Payton's second season, reaching the NFL playoffs for the first time since the team won Super Bowl 50 following the 2015 campaign. Payton's squad has now clinched another playoff berth -- and they have aspirations to go much further than the Wild Card round this time.

For Week 16 NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 16 NFL schedule here. After analyzing every game in Week 16, the AI says the Broncos (-3.5, 46.5), who have won 11 in a row, cover comfortably against the Jaguars .

It's no secret that the Kansas City Chiefs are in perhaps their most vulnerable regular season of the Patrick Mahomes era. They're 5-5, currently the 9th seed in the AFC, and have lost to all four AFC playoff teams they've played (Chargers, Jaguars, Bills ...

Arizona’s (7-3, 4-3 Big 12) defense set the tone with a tipped ball interception from cornerback Jay’Vion Cole that set up an early touchdown to put the Wildcats up 7-0 against the Bearcats. Although the game started off good for Arizona, its defense ...

The Washington Commanders are finally enjoying a bye week in NFL Week 12. Entering this weekend, the team has a disappointing 3-8 record. This season has been plagued by injuries, inconsistency, and flat-out underperformance in 2025. It's disappointing ...

This weekend's game could determine the No. 1 seed in the AFC, if the Chiefs win and the Bills lose. Here's a look at all remaining Week 16 games. 9-5 Texans at 13-1 Chiefs (-3.5), Saturday 1:00 p.m.